Medical Mysteries & Thrilling HistoriesUnpublished

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Thomas Mu tter was an audacious medical innovator who pioneered the use of ether as anaesthesia, the sterilisation of surgical tools and a compassion-based vision for helping the severely deformed, which clashed with the sentiments of the mid-nineteenth century. Brilliant, outspoken and handsome,...

"A best memoir of 2020" --BookPage The darkly funny memoir of Sarah Ramey's years-long battle with a mysterious illness that doctors thought was all in her head--but wasn't. A revelation and an inspiration for millions of women whose legitimate health complaints are...

A New York Times Bestseller Finalist for the 2022 Kirkus Prize | Named a best book of the year by The Guardian "Enthralling. Harrowing. Heartbreaking. And utterly redemptive. Lindsey Fitzharris hit this one out of the park." --Erik Larson, author of...

One of Literary Hub's Most Anticipated Books of 2025 A Goodreads Readers' Most Anticipated Fall Book From the New York Times bestselling author of Stiff and Fuzz, a rollicking exploration of the quest to re-create the impossible complexities of human...

The inspiration for the Netflix series Death by Lightning - now streaming! * NEW YORK TIMES BESTSELLER * The extraordinary account of James Garfield's rise from poverty to the American presidency, and the dramatic history of his assassination and legacy, from the bestselling author...

Drawing on her own medical experience as well as fifteen years of interviews with doctors, patients, researchers, and public health experts, O'Rourke's incisive new work speaks to an urgent subject: the epidemic scale of autoimmune disease in America (even greater with the advent of 'Long Covid')...

NEW YORK TIMES BESTSELLER * A NEW YORK TIMES NOTABLE BOOK OF THE YEAR * A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From...

#1 NEW YORK TIMES BESTSELLER * "The story of modern medicine and bioethics--and, indeed, race relations--is refracted beautifully, and movingly."--Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE * ONE OF THE "MOST...

NEW YORK TIMES BESTSELLER * The bestselling landmark account of the first emergence of the Ebola virus. * "This work of nonfiction is more terrifying than any sci-fi nightmare." --USA TODAY Also a mini-series drama starring Julianna Margulies, Topher Grace, Liam...

Selected as One of the Best Books of the 21st Century by The New York Times Winner of the Pulitzer Prize, adapted as a documentary from Ken Burns on PBS, this New York Times bestseller is "an extraordinary achievement" (The New Yorker)--a magnificent,...

Stiff is an oddly compelling, often hilarious exploration of the strange lives of our bodies postmortem. For two thousand years, cadavers--some willingly, some unwittingly--have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines,...

#1 NEW YORK TIMES BESTSELLER * OPRAH'S BOOK CLUB PICK * ONE OF GQ's TOP 50 BOOKS OF LITERARY JOURNALISM IN THE 21st CENTURY * The heartrending story of a midcentury American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in...

One of the New York Times's Best Ten Books of the Year Winner of the National Book Critics Circle Award for Nonfiction Winner of the 2014 J. Anthony Lukas Book Prize, the PEN/John Kenneth Galbraith Award, the Los Angeles Times Book Prize,...

NATIONAL BESTSELLER * The gripping story of Elizabeth Holmes and Theranos--one of the biggest corporate frauds in history--a tale of ambition and hubris set amid the bold promises of Silicon Valley, rigorously reported by the prize-winning journalist. With a new Afterword.

In his most extraordinary book, "one of the great clinical writers of the twentieth century" (The New York Times) recounts the case histories of patients lost in the bizarre, apparently inescapable world of neurological disorders. Oliver Sacks's The Man Who Mistook His Wife...

Now with a new Afterword from the author Winner of the National Book Critics Circle Award for Nonfiction The Spirit Catches You and You Fall Down explores the clash between a small county hospital in California and a refugee family from Laos over...

Most people want to avoid thinking about death, but Caitlin Doughty--a twenty-something with a degree in medieval history and a flair for the macabre--took a job at a crematory, turning morbid curiosity into her life's work. Thrown into a profession of gallows humor and vivid characters (both...

A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a "compelling" (The Washington Post) account of how Nobel Prize winner Jennifer Doudna...

A gripping memoir and medical suspense story about a young New York Post reporter's struggle with a rare and terrifying disease, opening a new window into the fascinating world of brain science. One day in 2009, twenty-four-year-old Susannah Cahalan woke up alone in a...

New York Times Bestseller New York Times Notable Book of 2016 * NPR Great Read of 2016 * Named a Best Book of 2016 by The Economist, Smithsonian, NPR's Science Friday, MPR, Minnesota Star Tribune, Kirkus Reviews,...

"America's funniest science writer" (Washington Post) takes us down the hatch on an unforgettable tour. The alimentary canal is classic Mary Roach terrain: the questions explored in Gulp are as taboo, in their way, as the cadavers in Stiff and every bit as surreal as the universe of zero gravity...

From the era of slavery to the present day, the first full history of black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. Medical Apartheidis the first and only comprehensive history of medical experimentation on...

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize-winning author of The Emperor of All Maladies--a fascinating history of the gene and "a magisterial account of...

Pulitzer Prize-winning science writer Deborah Blum follows New York City's first forensic scientists to discover a fascinating Jazz Age story of chemistry and detection, poison and murder. Deborah Blum, writing with the high style and skill for suspense that is characteristic of...

A thrilling account of the worst cholera outbreak in Victorian London and a brilliant exploration of how Dr John Snow's solution revolutionised the way people think about disease, cities, science and the modern world. This is an endlessly fascinating and compelling account of the summer of 1854,...

Val McDermid is one of the finest crime writers we have, whose novels have captivated millions of readers worldwide with their riveting narratives of characters who solve complex crimes and confront unimaginable evil. In the course of researching her bestselling novels McDermid has become...

Winner, 2018 PEN/E.O. Wilson Prize for Literary Science Writing Short-listed for the 2018 Wellcome Book Prize A Top 10 Science Book of Fall 2017, Publishers Weekly A Best History Book of 2017, The Guardian "Warning: She...

#1 New York Times bestseller "Barry will teach you almost everything you need to know about one of the deadliest outbreaks in human history."--Bill Gates "Monumental... an authoritative and disturbing morality tale."--Chicago Tribune The...

The mesmerizing basis of the movie starring Eddie Redmayne and Jessica Chastain⁠--a "stunning book...that should and does bring to mind In Cold Blood"--takes you inside the mind of America's most prolific serial killer, whose 16-year long "nursing" career left as many as 400 dead....

NEW YORK TIMES BESTSELLER * An urgent wake-up call about the future of emerging viruses and a gripping account of the doctors and scientists fighting to protect us, told through the story of the deadly 2013-2014 Ebola epidemic   "Crisis in the Red Zone...

From a Pulitzer Prize-winning historian comes a riveting history of New York's iconic public hospital that charts the turbulent rise of American medicine. Bellevue Hospital, on New York City's East Side, occupies a colorful and horrifying place in the public imagination: a den of...

National Book Award Finalist for Nonfiction A brilliant and courageous doctor reveals, in gripping accounts of true cases, the power and limits of modern medicine. Sometimes in medicine the only way to know what is truly going on in a patient is to operate,...

New York City, 1929. A sanatorium, a deadly disease, and a dire nurse shortage. So begins the remarkable true story of the Black nurses who helped cure one of the world's deadliest plagues: tuberculosis. During those dark pre-antibiotic days, when tuberculosis killed one in seven...

In the spirit of Oliver Sacks and the inspiration for the NBC drama New Amsterdam, this memoir from a Medical Director of Bellevue Hospital looks poignantly at patients' lives, highlighting the complex mind-body connection. "As intensely involving as any scripted...

At twelve, Howard Dully was guilty of the same crimes as other boys his age: he was moody and messy, rambunctious with his brothers, contrary just to prove a point, and perpetually at odds with his parents. Yet somehow, this normal boy became one of the youngest people on whom Dr. Walter Freeman...

The Instant New York Times best seller! Riveting. ... [Marsh] gives us an extraordinarily intimate, compassionate and sometimes frightening understanding of his vocation. - The New York Times Winner of the PEN Ackerley Prize Shortlisted for both the...

A young girl is perched on the cold chrome of yet another doctor’s examining table, missing yet another day of school. Just twelve, she’s tall, skinny, and weak. It’s four o’clock, and she hasn’t been allowed to eat anything all day. Her mother, on the other hand, seems...

A New York Times 2016 Notable Book The definitive history of the successful battle to halt the AIDS epidemic--from the creator of, and inspired by, the seminal documentary How to Survive a Plague. A riveting, powerful telling of the story of the...

This work presents an unflinching look inside the detective story that marks nearly every illness - the diagnosis - revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying.

A riveting true crime story that vividly recounts the birth of modern forensics. At the end of the nineteenth century, serial murderer Joseph Vacher, known and feared as “The Killer of Little Shepherds,” terrorized the French countryside. He eluded authorities for years...

"Oliver Sacks meets Stephen King"* in this propulsive, haunting journey into the life of the most studied human research subject of all time, the amnesic known as Patient H.M., a man who forever altered our understanding of how memory works--and whose treatment raises deeply unsettling questions...

The untold story of how America's Progressive-era war on smallpox sparked one of the great civil liberties battles of the twentieth century. At the turn of the last century, a powerful smallpox epidemic swept the United States from coast to coast. The age-old disease spread...

"Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the...

"Stories of human behavior at its most extreme....With humor, compassion, empathy, and insight, Small searches for and finds the humanity that lies hidden under even the most bizarre symptoms." --Daniel H. Pink, author of Drive and A Whole New Mind A psychiatrist's stories of...

* A People Best Book of the Year * Time and The Washington Post's Most Anticipated List * Longlisted for the Andrew Carnegie Medal for Excellence * From the MacArthur genius, two-time Pulitzer Prize finalist, and playwright, this "captivating, insightful...

"Delightfully horrifying."--Popular Science One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 This wryly humorous collection of stories about bizarre medical treatments and cases offers a unique portrait of a bygone era in...

For two hundred years a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness...

NEW YORK TIMES EDITORS' CHOICE * A "mesmerizing" (The New York Times Book Review) true story about a shocking crime and a mysterious illness that will forever change your notions of how we punish and how we heal--an expansion on one of the most popular This American Life...

In Sweden, hundreds of refugee children fall into a state that resembles sleep for months or years at a time. In Le Roy, a town in upstate New York, teenage girls develop involuntary twitches and seizures that spread like a conta­gion. In the U.S. Embassy in Cuba, employees experience headaches and...

SEMI-FINALIST FOR THE 2023 THURBER PRIZE FOR AMERICAN HUMOR *  "A fiery cultural critique." --Kirkus Reviews  *  "...a powerful, beautifully written, and utterly important book."--New York Journal of Books...

"An unforgettable nonfiction thriller, expertly reported....A tremendously revealing and twisted ride, where life and death are now mere cold cash commodities." --Michael Largo, author of Final Exits Award-winning investigative journalist and contributing Wired...

A Best Book of the Year: Real Simple, Entropy, Mental Floss, Bitch Media, The Paris Reivew, and LitHub. Time Magazine's Best Memoirs of 2018 * Boston Globe's 25 Books We Can't Wait to Read in 2018  *  Buzzfeed's 33 Most Exciting New Books  * GQ Best...

A harrowing memoir of one woman's extraordinary effort to save her husband's life--and the discovery of a forgotten cure that has the potential to save millions more. Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in...

For Chinese immigrant Wong Chut King, surviving in San Francisco meant a life in the shadows. His passing on March 6, 1900, would have been unremarkable if a city health officer hadn't noticed a swollen black lymph node on his groin--a sign of bubonic plague. Empowered by racist pseudoscience,...

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent,...

A leading neurologist recounts some of her most astonishing, challenging cases, which demonstrate how central the study of epilepsy has been to our understanding of the brain.   Brainstorm follows the stories of people whose medical diagnoses are so strange even their...

An award-winning investigative journalist's horrifying true crime story of America's deadliest drug contamination outbreak and the greed and deception that fueled it. Two pharmacists sit in a Boston courtroom accused of murder. The weapon: the fungus Exserohilum rostratum. The death count: 100 and...

In his acclaimed memoir Intern, Sandeep Jauhar chronicled the formative years of his residency at a prestigious New York City hospital. Doctored, his New York Times bestselling harrowing follow-up, observes the crisis of American medicine through the eyes of an attending...

How We Do Harm exposes the underbelly of healthcare today--the overtreatment of the rich, the under treatment of the poor, the financial conflicts of interest that determine the care that physicians' provide, insurance companies that don't demand the best (or even the least expensive) care...

"Cole-Adams blends research, reflection, and memoir to try to grapple with the meaning of consciousness . . . Cole-Adams presents a lyrical journey through the vital question of what it means to be human." --Kirkus Reviews Anesthetize: to render insensible

An epic story told by a unique voice in American medicine, One Doctor describes life-changing experiences in the career of a distinguished physician. An epic story told by a unique voice in Ameri­can medicine, One Doctor describes life-changing experiences in...

In the bestselling tradition of In the Heart of the Sea, The Colonyreveals the untold history of the infamous American leprosy colony on Molokai and of the extraordinary people who struggled to survive under the most horrific circumstances. In 1866, twelve men and women and one small child were...

When James Harrison was a 14 year old boy in Australia in the 1950s, he had emergency surgery and received a transfusion, which saved his life. Even though he hated needles, James felt a debt to the unknown strangers who'd given him such a gift and vowed to return the favor. Little did he know...

Intern is Sandeep Jauhar's story of his days and nights in residency at a busy hospital in New York City, a trial that led him to question our every assumption about medical care today. Residency--and especially the first year, called internship--is legendary for its brutality....

WHO DECIDES WHICH FACTS ARE TRUE? In 1998 Andrew Wakefield, a British gastroenterologist with a history of self-promotion, published a paper with a shocking allegation: the measles-mumps-rubella vaccine might cause autism. The media seized hold of the story and, in the process, helped...

"A renowned geneticist races against time to diagnose a malady that landed at his door... A complex, well-related story of medical detective work." --KIRKUS     At the age of twenty-seven, Whitney Dafoe was forced to give up his life as a photographer...

BRILLIANTLY EXPLORING TODAY'S CUTTING-EDGE BRAIN RESEARCH, MIND WIDE OPEN IS AN UNPRECEDENTED JOURNEY INTO THE ESSENCE OF HUMAN PERSONALITY, ALLOWING READERS TO UNDERSTAND THEMSELVES AND THE PEOPLE IN THEIR LIVES AS NEVER BEFORE. Using a mix of experiential reportage, personal...

FINALIST FOR THE 2022 PEN/E.O. WILSON LITERARY SCIENCE WRITING AWARD "Aguirre writes clearly, concisely, and often cinematically. The book succeeds in providing an accessible yet substantive look at memory science and offering glimpses of the often-challenging process of...